O2 sensor will cause the code but not a misfire...
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Just remembered something. We used to put plastic wire loom over all our ignition wires. After having a few vehicles with misfire codes and shorted coils, we started putting it on all our vehicles (private fleet). If an ignition wire rides on a ground source such as a valve cover long enough, the wire insulation breaks down and allows a partial ground. That leaves you with a weak charge going to the spark plug and a not so hot spark. Electronics are weird and the thing that you think would never cause a problem actually could. Also, an ignition wire thats been grounding for a while will have a white dusty substance around that portion of the wire and the object its been grounding on. I dont know what it is but its a by-product of a high voltage short..
Its called Corona.
Update:
The Jeep has been running unusually bad for the past week. Same symptoms as usual, just worse, so I went ahead and rechecked my codes this evening. Has three: P0135, P0301 (always has that one) and P0455.
The P0135 references the upstream O2 sensor, bank 1, I believe. Somebody on the Jeep forum I'm asking questions on had already suggested looking at the O2 sensors, so I'll go ahead and replace both upstream sensors tomorrow and see how it does.
Thanks!