for all of you freaking out

Not many people have died in Italy have they. How does this compare to the flu deaths over there from last year? Only 10,000 people have died in Italy from Covid so far. That video says this high number is due to air pollution. Almost 1000 people died yesterday alone. I guess you could redo these numbers.
 
TRoland said:
No. The dumbasses that do not see it now will never see it. They willingly lay under the blanket of the dems with ear plugs lol. It’s real! And it so serious! There’s a huge problem at hand and it’s not the corona. And it amazes me how many people are blind to it. And how big of a cover up scandal it really is! Trump has the opportunity to pull the plug on them. If he lives to watch the thing unfold is the question. Surprised he’s still around
Click to expand...

And Trump is the seeing eye dog.
 
bambam said:
Not many people have died in Italy have they. How does this compare to the flu deaths over there from last year? Only 10,000 people have died in Italy from Covid so far. That video says this high number is due to air pollution. Almost 1000 people died yesterday alone. I guess you could redo these numbers.
Click to expand...
compare it to germany or a neighboring country where the numbers are drastically lower
 
GeauxLSU said:
If their eyes aren't opened already, they'll NEVER be opened. My prediction: This will blow over far enough in advance of the elections, despite the media's best attempts to keep it alive, and the market will rebound quickly, and Trump will be re-elected. Life will go on. Eventually the house of cards will crumble and this will simply be several of the too many cards that caused it.
Click to expand...
This is what I HOPE happens and believe can happen. But, there's so many folks not taking any precautions at all that are the one's that potentially turn this thing into something actually very big. Just saying.
 
Here is a lot of interesting reading.The reference links work, so this is a tremendous amount of information. Below is the main link. Click "Article" in the links below to go to other reference articles.

https://www.nature.com/articles/nm....XDBAZF7DhHNHfk8AHdDwUTfRxXora7cHRbCUCBICcqyL0


References
  1. 1
    Ge, X.Y. et al. Isolation and characterization of a bat SARS-like coronavirus that uses the ACE2 receptor. Nature 503, 535–538 (2013).
  2. 2
    Yount, B. et al. Reverse genetics with a full-length infectious cDNA of severe acute respiratory syndrome coronavirus. Proc. Natl. Acad. Sci. USA 100, 12995–13000 (2003).
  3. 3
    Becker, M.M. et al. Synthetic recombinant bat SARS-like coronavirus is infectious in cultured cells and in mice. Proc. Natl. Acad. Sci. USA 105, 19944–19949 (2008).
  4. 4
    Peiris, J.S., Guan, Y. & Yuen, K.Y. Severe acute respiratory syndrome. Nat. Med. 10, S88–S97 (2004).
  5. 5
    Al-Tawfiq, J.A. et al. Surveillance for emerging respiratory viruses. Lancet Infect. Dis. 14, 992–1000 (2014).
  6. 6
    He, B. et al. Identification of diverse alphacoronaviruses and genomic characterization of a novel severe acute respiratory syndrome–like coronavirus from bats in China. J. Virol. 88, 7070–7082 (2014).
  7. 7
    Li, F. Receptor recognition and cross-species infections of SARS coronavirus. Antiviral Res. 100, 246–254 (2013).
  8. 8
    Sheahan, T. et al. Mechanisms of zoonotic severe acute respiratory syndrome coronavirus host range expansion in human airway epithelium. J. Virol. 82, 2274–2285 (2008).
  9. 9
    Yoshikawa, T. et al. Dynamic innate immune responses of human bronchial epithelial cells to severe acute respiratory syndrome–associated coronavirus infection. PLoS ONE 5, e8729 (2010).
  10. 10
    Qiu, X. et al. Reversion of advanced Ebola virus disease in nonhuman primates with ZMapp. Nature 514, 47–53 (2014).
  11. 11
    Sui, J. et al. Broadening of neutralization activity to directly block a dominant antibody-driven SARS-coronavirus evolution pathway. PLoS Pathog. 4, e1000197 (2008).
  12. 12
    Sui, J. et al. Effects of human anti–spike protein receptor binding domain antibodies on severe acute respiratory syndrome coronavirus neutralization escape and fitness. J. Virol. 88, 13769–13780 (2014).
  13. 13
    Rockx, B. et al. Escape from human monoclonal antibody neutralization affects in vitro and in vivo fitness of severe acute respiratory syndrome coronavirus. J. Infect. Dis. 201, 946–955 (2010).
  14. 14
    Spruth, M. et al. A double-inactivated whole-virus candidate SARS coronavirus vaccine stimulates neutralizing and protective antibody responses. Vaccine 24, 652–661 (2006).
  15. 15
    Bolles, M. et al. A double-inactivated severe acute respiratory syndrome coronavirus vaccine provides incomplete protection in mice and induces increased eosinophilic proinflammatory pulmonary response upon challenge. J. Virol. 85, 12201–12215 (2011).
  16. 16
    Siegrist, C.-A. in Vaccines 6th edn. (eds. Plotkin, S.A., Orenstein, W.A. & Offit, P.A.) 14–32 (W.B. Saunders, 2013).

  17. 17
    Deming, D. et al. Vaccine efficacy in senescent mice challenged with recombinant SARS-CoV bearing epidemic and zoonotic spike variants. PLoS Med. 3, e525 (2006).
  18. 18
    Graham, R.L., Donaldson, E.F. & Baric, R.S. A decade after SARS: strategies for controlling emerging coronaviruses. Nat. Rev. Microbiol. 11, 836–848 (2013).
  19. 19
    Graham, R.L. & Baric, R.S. Recombination, reservoirs and the modular spike: mechanisms of coronavirus cross-species transmission. J. Virol. 84, 3134–3146 (2010).
  20. 20
    Agnihothram, S. et al. A mouse model for betacoronavirus subgroup 2c using a bat coronavirus strain HKU5 variant. MBio 5, e00047-14 (2014).
  21. 21
    Relman, D.A. Metagenomics, infectious disease diagnostics and outbreak investigations: sequence first, ask questions later? J. Am. Med. Assoc. 309, 1531–1532 (2013).
  22. 22
    Kaiser, J. Moratorium on risky virology studies leaves work at 14 institutions in limbo. ScienceInsider http://news.sciencemag.org/biology/...ogy-studies-leaves-work-14-institutions-limbo (2014).

  23. 23
    Frieman, M. et al. Molecular determinants of severe acute respiratory syndrome coronavirus pathogenesis and virulence in young and aged mouse models of human disease. J. Virol. 86, 884–897 (2012).
  24. 24
    Ren, W. et al. Difference in receptor usage between severe acute respiratory syndrome (SARS) coronavirus and SARS-like coronavirus of bat origin. J. Virol. 82, 1899–1907 (2008).
  25. 25
    Sims, A.C. et al. Release of severe acute respiratory syndrome coronavirus nuclear import block enhances host transcription in human lung cells. J. Virol. 87, 3885–3902 (2013).
  26. 26
    Fulcher, M.L., Gabriel, S., Burns, K.A., Yankaskas, J.R. & Randell, S.H. Well-differentiated human airway epithelial cell cultures. Methods Mol. Med. 107, 183–206 (2005).
  27. 27
    Roberts, A. et al. A mouse-adapted SARS-coronavirus causes disease and mortality in BALB/c mice. PLoS Pathog. 3, e5.
 
bambam said:
Here is a lot of interesting reading.The reference links work, so this is a tremendous amount of information. Below is the main link. Click "Article" in the links below to go to other reference articles.

https://www.nature.com/articles/nm....XDBAZF7DhHNHfk8AHdDwUTfRxXora7cHRbCUCBICcqyL0


References
  1. 1
    Ge, X.Y. et al. Isolation and characterization of a bat SARS-like coronavirus that uses the ACE2 receptor. Nature 503, 535–538 (2013).
  2. 2
    Yount, B. et al. Reverse genetics with a full-length infectious cDNA of severe acute respiratory syndrome coronavirus. Proc. Natl. Acad. Sci. USA 100, 12995–13000 (2003).
  3. 3
    Becker, M.M. et al. Synthetic recombinant bat SARS-like coronavirus is infectious in cultured cells and in mice. Proc. Natl. Acad. Sci. USA 105, 19944–19949 (2008).
  4. 4
    Peiris, J.S., Guan, Y. & Yuen, K.Y. Severe acute respiratory syndrome. Nat. Med. 10, S88–S97 (2004).
  5. 5
    Al-Tawfiq, J.A. et al. Surveillance for emerging respiratory viruses. Lancet Infect. Dis. 14, 992–1000 (2014).
  6. 6
    He, B. et al. Identification of diverse alphacoronaviruses and genomic characterization of a novel severe acute respiratory syndrome–like coronavirus from bats in China. J. Virol. 88, 7070–7082 (2014).
  7. 7
    Li, F. Receptor recognition and cross-species infections of SARS coronavirus. Antiviral Res. 100, 246–254 (2013).
  8. 8
    Sheahan, T. et al. Mechanisms of zoonotic severe acute respiratory syndrome coronavirus host range expansion in human airway epithelium. J. Virol. 82, 2274–2285 (2008).
  9. 9
    Yoshikawa, T. et al. Dynamic innate immune responses of human bronchial epithelial cells to severe acute respiratory syndrome–associated coronavirus infection. PLoS ONE 5, e8729 (2010).
  10. 10
    Qiu, X. et al. Reversion of advanced Ebola virus disease in nonhuman primates with ZMapp. Nature 514, 47–53 (2014).
  11. 11
    Sui, J. et al. Broadening of neutralization activity to directly block a dominant antibody-driven SARS-coronavirus evolution pathway. PLoS Pathog. 4, e1000197 (2008).
  12. 12
    Sui, J. et al. Effects of human anti–spike protein receptor binding domain antibodies on severe acute respiratory syndrome coronavirus neutralization escape and fitness. J. Virol. 88, 13769–13780 (2014).
  13. 13
    Rockx, B. et al. Escape from human monoclonal antibody neutralization affects in vitro and in vivo fitness of severe acute respiratory syndrome coronavirus. J. Infect. Dis. 201, 946–955 (2010).
  14. 14
    Spruth, M. et al. A double-inactivated whole-virus candidate SARS coronavirus vaccine stimulates neutralizing and protective antibody responses. Vaccine 24, 652–661 (2006).
  15. 15
    Bolles, M. et al. A double-inactivated severe acute respiratory syndrome coronavirus vaccine provides incomplete protection in mice and induces increased eosinophilic proinflammatory pulmonary response upon challenge. J. Virol. 85, 12201–12215 (2011).
  16. 16
    Siegrist, C.-A. in Vaccines 6th edn. (eds. Plotkin, S.A., Orenstein, W.A. & Offit, P.A.) 14–32 (W.B. Saunders, 2013).

  17. 17
    Deming, D. et al. Vaccine efficacy in senescent mice challenged with recombinant SARS-CoV bearing epidemic and zoonotic spike variants. PLoS Med. 3, e525 (2006).
  18. 18
    Graham, R.L., Donaldson, E.F. & Baric, R.S. A decade after SARS: strategies for controlling emerging coronaviruses. Nat. Rev. Microbiol. 11, 836–848 (2013).
  19. 19
    Graham, R.L. & Baric, R.S. Recombination, reservoirs and the modular spike: mechanisms of coronavirus cross-species transmission. J. Virol. 84, 3134–3146 (2010).
  20. 20
    Agnihothram, S. et al. A mouse model for betacoronavirus subgroup 2c using a bat coronavirus strain HKU5 variant. MBio 5, e00047-14 (2014).
  21. 21
    Relman, D.A. Metagenomics, infectious disease diagnostics and outbreak investigations: sequence first, ask questions later? J. Am. Med. Assoc. 309, 1531–1532 (2013).
  22. 22
    Kaiser, J. Moratorium on risky virology studies leaves work at 14 institutions in limbo. ScienceInsider http://news.sciencemag.org/biology/...ogy-studies-leaves-work-14-institutions-limbo (2014).

  23. 23
    Frieman, M. et al. Molecular determinants of severe acute respiratory syndrome coronavirus pathogenesis and virulence in young and aged mouse models of human disease. J. Virol. 86, 884–897 (2012).
  24. 24
    Ren, W. et al. Difference in receptor usage between severe acute respiratory syndrome (SARS) coronavirus and SARS-like coronavirus of bat origin. J. Virol. 82, 1899–1907 (2008).
  25. 25
    Sims, A.C. et al. Release of severe acute respiratory syndrome coronavirus nuclear import block enhances host transcription in human lung cells. J. Virol. 87, 3885–3902 (2013).
  26. 26
    Fulcher, M.L., Gabriel, S., Burns, K.A., Yankaskas, J.R. & Randell, S.H. Well-differentiated human airway epithelial cell cultures. Methods Mol. Med. 107, 183–206 (2005).
  27. 27
    Roberts, A. et al. A mouse-adapted SARS-coronavirus causes disease and mortality in BALB/c mice. PLoS Pathog. 3, e5.
Click to expand...
Holy wall of text bambam bambam !
 
MNRSports said:
This is what I HOPE happens and believe can happen. But, there's so many folks not taking any precautions at all that are the one's that potentially turn this thing into something actually very big. Just saying.
Click to expand...
According to the dooms-dayers last month we should've already been dead by now but the end of time always seems to be pushed out a week or month. It's time for every one to chill the **** out and stop the fear mongering
 
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